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Cellular Endocrinology in Health and Disease by Alfredo Ulloa-Aguirre, P. Michael Conn

By Alfredo Ulloa-Aguirre, P. Michael Conn

Cellular Endocrinology in healthiness and Disease describes the underlying foundation of endocrine functionality, supplying a massive software to appreciate the basics of endocrine illnesses. offering a complete overview of the elemental technology of endocrinology, from mobilephone biology to human sickness, this paintings explores and dissects the functionality of a few mobile platforms. between those are these whose functionality used to be now not visible till lately, together with the endocrine features of bone and the adipose tissue.

Providing content material that crosses disciplines, Cellular Endocrinology in well-being and Disease information how mobile endocrine functionality contributes to procedure body structure and mediates endocrine issues. A tools part proves novel and priceless techniques throughout study concentration that would be beautiful to clinical scholars, citizens, and experts within the box of endocrinology, in addition to to these drawn to mobile legislation. Editors Alfredo Ulloa-Aguirre and P. Michael Conn, specialists in molecular and mobile elements of endocrinology, convey contributions rigorously chosen for relevance, influence, and readability of expression from prime box experts. 

  • Covers systemic endocrine motion on the mobile point in either healthiness and disease
  • Delivers details at the integration of mobilephone identification and endocrinology
  • Incorporates fresh advancements in endocrinology to supply an updated connection with researchers

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Existence of long-lasting experience-dependent plasticity in endocrine cell networks. Nat Commun 2012;3:605. 2 The parathyroids are small glands, numbering four or more, and originally took this name because of their close proximity to the thyroid, sharing the same location and vascular supply. The parathyroids originate from the endoderm of the third and the fourth pharyngeal pouches, with the contribution of neural crest cells in the pharyngeal arches, in a progression that includes the formation, migration and differentiation towards mature glands.

Vergara LA, Stojilkovic SS, Rojas E. GnRH-induced cytosolic calcium oscillations in pituitary gonadotrophs: phase resetting by membrane depolarization. Biophys J 1995;69:1606À14. 34. Kukuljan M, Vergara L, Stojilkovic SS. Modulation of the kinetics of inositol 1,4,5-trisphosphate-induced [Ca21]i oscillations by calcium entry in pituitary gonadotrophs. Biophys J 1997;72(2 Pt 1):698À707. 35. Denef C. Paracrinicity: the story of 30 years of cellular pituitary crosstalk. J Neuroendocrinol 2008;20:1À70.

Cellular and molecular specificity of pituitary gland physiology. Physiol Rev 2012;92:1À38. 6. Roudbaraki M, Lorsignol A, Langouche L, Callewaert G, Vankelecom H, Denef C. Target cells of gamma3-melanocyte-stimulating hormone detected through intracellular Ca21 responses in inmature rat pituitary constitute a fraction of all main pituitary cell types, but mostly express multiple hormone phenotypes at the messenger ribonucleic acid level. Refractoriness to melanocortin-3 receptor blockade in the lacto-somatotroph lineage.

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