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Calcium Metabolism, Bone and Metabolic Bone Diseases by C. A. Baud, J. A. Pouëzat (auth.), Friedrich Kuhlencordt Dr.

By C. A. Baud, J. A. Pouëzat (auth.), Friedrich Kuhlencordt Dr. med., Hans-Peter Kruse Dr. med. (eds.)

The X. ecu Symposium on Calcified Tissues happened in Hamburg from sixteenth to 21 st September 1973. The monetary backing got here from the Gesund­ heitsbehorde der Freien und Hansestadt Hamburg (President Dr. Zylmann), the Bundesministerium fur Jugend, Familie und Gesundheit, and from undefined. This made it attainable to hold out the medical software, to ask a number of eu and non-European scientists, and to arrange a social application designed to set up own touch among delegates and to make viewers conversant in our state. within the identify of the organizing committee, we herewith exhibit our warmest appreciation of the entire support given to us. Professor Bartelheimer, because the consultant of the clinical college and on behalf of the President of the collage of Hamburg, welcomed the Parti­ cipants within the symposium to our urban. The background of those conferences started in Oxford in 1963, with the 1st eu Bone and teeth Symposium, geared up via H. J. J. Blackwood, B. E. C. Nordin, and Dame Janet Vaughan. the assumption was once to present in Europe an establishment simi­ lar to the yankee Gordon study meetings of Bone and enamel. After the U. okay. , the host international locations have been Belgium, Switzerland, the Netherlands, France, Sweden, Italy, Israel and Austria. the second one symposium in Liege already bore the current name.

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Thyroidectomized, supplied with {-thyroxine in the food and bearing functional parathyroid autografts, did as well as euthyroid controls with functional parathyroid autografts, as far as steady-state plasma calcium control is concerned. Calcitonin removal had no significant effect on either intensity or relative regulatory importance of v o + and v o -' nor did it affect in any major way the calcium and phosphorus content of the long bones. Finally, urinary calcium excretion was unaffected by calcitonin removal and the relative regulatory importance of bone and kidney was unchanged, bone retaining its primary role in rats deprived of calcitonin.

All operational blocks can be considered as analogous computing elements The optimisation of the analogous model was performed on a computer EAI 580 using a quadratic function to minimize the instantaneous error. With this technique, we can extract the numerical values of parameters of a non-steady differential system of high order, direct resolution of which would be rather difficult and sometimes impossible. The initial model (Fig. 1) reproduced the mean value of the real 45Ca plasma curve from the 36 th hour on to the 8th day.

KI DN EY +,-E Vu Fig. 2. e. calcium load from gut) mg Ca/day v o + = bone calcium deposition, ~g/day v o - = bone calcium resorption, mg/day v fi = calcium filtered in kidney, mg/day calcium reabsorbed in kidney, mg/day calcium secreted in kidney, mg/day plasma calcium concentration, mg/100 ml plasma calcium reference value, mg/100 ml error, Le. ~aJ - [u] 17 When calcium enters the bloodstream via absorption from the intestine, it tends to raise the plasma calcium-COncentration ~aJ, drawn as a signal being compared in a comparator with a "set" or "reference" value, ~].

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